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Syed R Husain Selected Research

IL13-PE38

8/2010Phase III randomized trial of CED of IL13-PE38QQR vs Gliadel wafers for recurrent glioblastoma.
3/2009IL-13 cytotoxin has potent antitumor activity and synergizes with paclitaxel in a mouse model of oral squamous cell carcinoma.
4/2006Safety of intraparenchymal convection-enhanced delivery of cintredekin besudotox in early-phase studies.
8/2002Improved anti-tumor activity and safety of interleukin-13 receptor targeted cytotoxin by systemic continuous administration in head and neck cancer xenograft model.

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Syed R Husain Research Topics

Disease

26Neoplasms (Cancer)
01/2022 - 07/2002
6Glioma (Gliomas)
06/2006 - 10/2003
5Breast Neoplasms (Breast Cancer)
01/2022 - 05/2003
4Pancreatic Neoplasms (Pancreatic Cancer)
01/2022 - 07/2002
4Glioblastoma (Glioblastoma Multiforme)
01/2022 - 12/2004
4Squamous Cell Carcinoma of Head and Neck
03/2014 - 01/2006
4Brain Neoplasms (Brain Tumor)
03/2009 - 12/2004
2Ovarian Neoplasms (Ovarian Cancer)
01/2019 - 09/2006
2Head and Neck Neoplasms (Head and Neck Cancer)
02/2013 - 08/2002
2Melanoma (Melanoma, Malignant)
07/2012 - 11/2010
2Sarcoma (Soft Tissue Sarcoma)
11/2011 - 11/2010
2Adenocarcinoma
01/2010 - 10/2007
2Fibrosis (Cirrhosis)
10/2008 - 01/2006
2Lung Neoplasms (Lung Cancer)
01/2006 - 11/2002
1Colorectal Neoplasms (Colorectal Cancer)
01/2022
1Adrenocortical Carcinoma
01/2022
1Spinal Cord Injuries (Spinal Cord Injury)
07/2018
1Weight Loss (Weight Reduction)
02/2013
1Neoplasm Metastasis (Metastasis)
11/2011
1Mouth Neoplasms (Oral Cancer)
03/2009
1Non-alcoholic Fatty Liver Disease
10/2008
1Liver Cirrhosis (Hepatic Cirrhosis)
10/2008
1Disease Progression
10/2007
1Cachexia
09/2006
1Asthma (Bronchial Asthma)
01/2006
1Kaposi Sarcoma (Kaposi's Sarcoma)
01/2006
1Acquired Immunodeficiency Syndrome (AIDS)
01/2006
1Hypersensitivity (Allergy)
01/2006
1Malignant Mesothelioma
08/2004
1Mesothelioma
08/2004
1Necrosis
10/2003
1Prostatic Neoplasms (Prostate Cancer)
03/2003
1Prostatic Hyperplasia (Benign Prostatic Hyperplasia)
03/2003
1Carcinoma (Carcinomatosis)
03/2003
1Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
11/2002

Drug/Important Bio-Agent (IBA)

17Cytotoxins (Cytolysins)IBA
11/2011 - 07/2002
15Interleukin-13IBA
01/2022 - 08/2002
10Interleukin-13 Receptors (Interleukin 13 Receptor)IBA
01/2022 - 08/2002
10ExotoxinsIBA
01/2019 - 03/2003
8Interleukin-4 (Interleukin 4)IBA
01/2019 - 11/2002
7Pharmaceutical PreparationsIBA
03/2009 - 08/2002
6Interleukin-4 Receptors (Interleukin 4 Receptor)IBA
10/2007 - 07/2002
5Proteins (Proteins, Gene)FDA Link
04/2012 - 10/2003
4CytokinesIBA
01/2022 - 10/2003
4AntigensIBA
01/2022 - 10/2003
4Immunotoxins (Immunotoxin)IBA
02/2013 - 04/2006
4Cell Surface ReceptorsIBA
04/2012 - 10/2003
4IL13-PE38IBA
08/2010 - 08/2002
4InterleukinsIBA
04/2006 - 07/2002
3InterferonsIBA
01/2019 - 07/2012
3Neoplasm Antigens (Tumor Antigens)IBA
02/2013 - 01/2010
2Cancer VaccinesIBA
04/2012 - 11/2011
2DNA (Deoxyribonucleic Acid)IBA
11/2011 - 11/2010
2DNA VaccinesIBA
11/2011 - 11/2010
2poliferprosan 20 drug combination carmustine (Gliadel)FDA Link
08/2010 - 04/2006
2Interleukin-13 Receptor alpha2 SubunitIBA
01/2010 - 09/2006
2Biomarkers (Surrogate Marker)IBA
09/2006 - 01/2006
2Pseudomonas aeruginosa Exotoxin AIBA
04/2006 - 10/2003
2interleukin-4-Pseudomonas exotoxinIBA
10/2003 - 07/2002
2Recombinant Fusion ProteinsIBA
10/2003 - 05/2003
1CollagenIBA
03/2014
1GelsIBA
03/2014
1Transforming Growth Factors (Transforming Growth Factor)IBA
02/2013
1TensinsIBA
02/2013
1Phosphoric Monoester Hydrolases (Phosphatases)IBA
02/2013
1Transforming Growth Factor-beta Type I ReceptorIBA
02/2013
1Interleukin-12 (IL 12)IBA
07/2012
1Hemagglutinins (Hemagglutinin)IBA
04/2012
1VaccinesIBA
11/2010
1ChemokinesIBA
11/2010
1Carmustine (FIVB)FDA Link
08/2010
1Transcription Factor AP-1 (Transcription Factor AP 1)IBA
01/2010
1Transforming Growth Factor beta (TGF-beta)IBA
01/2010
1Transforming Growth Factor beta1 (TGF beta 1)IBA
01/2010
1taxaneIBA
03/2009
1Paclitaxel (Taxol)FDA LinkGeneric
03/2009
1Hydroxyproline (4 Hydroxyproline)IBA
10/2008
1EnzymesIBA
10/2008
1Green Fluorescent ProteinsIBA
10/2007
1GemcitabineFDA Link
10/2007
1Cytokine Receptors (Cytokine Receptor)IBA
04/2006
1Interleukin-13 Receptor alpha1 SubunitIBA
01/2006
1Cytostatic AgentsIBA
10/2003
1Member 1 Subfamily B ATP Binding Cassette TransporterIBA
10/2003
1Multidrug Resistance-Associated ProteinsIBA
10/2003
1Antineoplastic Agents (Antineoplastics)IBA
10/2003
1multidrug resistance-associated protein 1IBA
10/2003
1Complementary DNA (cDNA)IBA
10/2003
1Carrier Proteins (Binding Protein)IBA
05/2003
1AndrogensIBA
03/2003
1Messenger RNA (mRNA)IBA
03/2003

Therapy/Procedure

17Therapeutics
01/2022 - 07/2002
5Immunotherapy
01/2022 - 11/2010
3Injections
12/2004 - 07/2002
2Catheters
08/2010 - 04/2006
1Exoskeleton Device
07/2018
1Operative Surgical Procedures
04/2006